Decreased VIP Content in Peripheral Nerve From Streptozocin-Induced Diabetic Rats

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Decreased VIP content in peripheral nerve from streptozocin-induced diabetic rats.

After induction of diabetes with streptozocin (STZ-D) in rats, we measured vasoactive intestinal polypeptide (VIP) content in sciatic nerve and spinal cord obtained from nondiabetic, untreated STZ-D, and insulin-treated STZ-D rats. Eight weeks after the onset of diabetes, caudal nerve conduction velocity (NCV) in the untreated STZ-D rats (n = 13) was slower than in the controls (n = 11; mean +/...

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ژورنال

عنوان ژورنال: Diabetes

سال: 1990

ISSN: 0012-1797,1939-327X

DOI: 10.2337/diab.39.5.608